www.jamanetwork.com/journals/jamainternalmedicine/...
Journal of the American Medical Association - February 18, 2022
Efficacy of Ivermectin Treatment on Disease Progression Among Adults With Mild to Moderate COVID-19 and Comorbidities The I-TECH Randomized Clinical Trial
"In this randomized clinical trial of high-risk patients with mild to moderate COVID-19, ivermectin treatment during early illness did not prevent progression to severe disease. The study findings do not support the use of ivermectin for patients with COVID-19."
www.marketwatch.com/story/you-will-not-believe-wha...
'You will not believe what I've just found.'
Inside the ivermectin saga: a hacked password, mysterious websites and faulty data.
Last Updated: Feb. 7, 2022 at 10:52 a.m. ET
First Published: Feb. 7, 2022 at 8:20 a.m. ET
By Jaimy Lee
How a drug used to treat parasites for decades became the hot and controversial drug of the pandemic
.... no comprehensive clinical trials have found that ivermectin works as a COVID-19 treatment. To make this issue even more complicated, no "gold standard" studies have yet found explicitly that it's useless against COVID-19 or that it's harmful to people taking it.
The ivermectin saga shows how the American drug regulatory system has been overrun by the pressures of the pandemic, including the rush to put out new research and then act immediately on those findings.
.... At a Senate hearing on Dec. 8, 2020, three days before the first COVID-19 vaccine was authorized in the U.S., Kory's testimony described ivermectin as a "miracle drug" that could be used more quickly than the vaccines, which would take months to roll out. His testimony several times referenced the Benha University preprint promising major clinical benefits, and video of the testimony went viral on YouTube.
"Nearly all studies are demonstrating the therapeutic potency and safety of ivermectin in preventing transmission and progression of illness in nearly all who take the drug," Kory wrote in his prepared testimony.
[note: the "Benha" study was done in Egypt and claimed remarkable success with ivermectin for covid patients. Unfortunately, the study seems to have been completely made up from nothing, never done, and the paper has since been withdrawn.]
.... Kory now says the Benha study is deeply flawed — "that paper stinks," he told me — but he puts the blame for the wave of retractions and withdrawals of ivermectin studies on pharmaceutical companies that he said have spent decades developing disinformation campaigns that aim to restrict the repurposing of cheap generic drugs.
"It would dry up the sales of remdesivir and Paxlovid and molnupiravir," said Kory, referring to some of the most prominent therapeutics, developed by Gilead, Pfizer PFE, +0.40% and Merck & Co. MRK, -1.25%, which have been authorized to treat COVID-19. "You name it. Monoclonal antibodies. It literally threatened the market value of almost anything out there on a global pandemic." Kory added: "What we're talking about, a historic corruption, the disinformation campaign waged against a repurposed drug."
https://respectfulinsolence.com/tag/ivermectin/
several articles by Dr. David Gorski
https://respectfulinsolence.com/2021/10/18/ivermec...
Ivermectin is the new hydroxychloroquine, take 7:
Are there positive studies that aren't fraudulent?
Ivermectin is the new hydroxychloroquine, a drug repurposed for COVID-19 that almost certainly doesn't work but is still being touted as a "miracle cure" by quacks, grifters, and political ideologues. Are the data supporting it all fraudulent and/or biased? The answer, increasingly, appears to be yes.
October 18, 2021
https://journals.lww.com/americantherapeutics/Full...
Meta_Analyses_Do_Not_Establish_Improved_Mortality.11.aspx
Meta-Analyses Do Not Establish Improved Mortality With Ivermectin Use in COVID-19
Rothrock, Steven G. MD1,2,*; Weber, Kurt D. MD3; Giordano, Philip A. MD3; Barneck, Mitchell D. MD3
American Journal of Therapeutics: January/February 2022 - Volume 29 - Issue 1 - p e87-e94
doi: 10.1097/MJT.0000000000001461
Ivermectin has been identified as an inexpensive, readily available drug with the potential to be repurposed as a treatment for COVID-19, especially in countries with limited access to vaccines. Although multiple studies have been published in an attempt to evaluate its usefulness in COVID-19, many are small and not constructed appropriately to detect differences in important clinical outcomes (ie, death). For this reason, researchers have turned to meta-analyses to combine study results and draw summary conclusions regarding ivermectin's effectiveness. Two such meta-analyses recently published in the American Journal of Therapeutics concluded that ivermectin decreased mortality and improved other surrogate end points in COVID-19.1–4 A recently withdrawn article caused both authors to rework their meta-analyses without altering their main conclusions.1–5 We feel that shortcomings within both sets of meta-analyses and limitations in the component studies are significant enough to invalidate their main finding that ivermectin reduces mortality. A review of other meta-analyses on the same subject, containing many of the same individual studies, were similarly limited by poor design.
https://journals.sagepub.com/doi/10.1177/088506662...
Retraction Notice
First Published November 9, 2021 Retraction
https://doi.org/10.1177/08850666211049062
RETRACTED: Clinical and Scientific Rationale for the “MATH+” Hospital Treatment Protocol for COVID-19
At the request of the Journal Editor and the Publisher, the following article has been retracted.
Kory P, Meduri GU, Iglesias J, Varon J, & Marik PE. Clinical and Scientific Rationale for the “MATH+” Hospital Treatment Protocol for COVID-19. J Intensive Care Med. 2021:36;135-156. 10.1177/0885066620973585
The article has been retracted after the journal received notice from Sentara Norfolk General Hospital in Norfolk, Virginia (“Sentara”) raising concerns about the accuracy of COVID-19 hospital mortality data reported in the article pertaining to Sentara.
https://www.sorryantivaxxer.com/post/ryan-ograyens...
didmyresearch3xvaxxed
The drug name should be changed to "Imavictim" given all the caterwauling about it.
www.buzzfeednews.com/article/stephaniemlee/ivermec...
A Prominent Study Said Ivermectin Prevents COVID, But The Data Is Suspect
An influential study from Argentina has been used to argue that ivermectin prevents COVID 100% of the time — but its inconsistencies have led experts to question if it could have actually happened as advertised.
Stephanie M. Lee
BuzzFeed News Reporter
Ken Bensinger
BuzzFeed News Reporter
Last updated on September 27, 2021, at 6:12 p.m. ET
Posted on September 2, 2021, at 6:03 p.m. ET
www.businessinsider.com/why-ivermectin-being-used-...
2 fringe doctors created the myth that ivermectin is a 'miracle cure' for COVID-19 — whipping up false hope that could have deadly consequences
Hilary Brueck
Sep 17, 2021
www.cochranelibrary.com/cdsr/doi/10.1002/14651858....
Ivermectin for preventing and treating COVID?19
Maria Popp, Miriam Stegemann, Maria-Inti Metzendorf, Susan Gould, Peter Kranke, Patrick Meybohm, Nicole Skoetz, Stephanie Weibel
published: 28 July 2021 Version history https://doi.org/10.1002/14651858.CD015017.pub
Based on the current very low? to low?certainty evidence, we are uncertain about the efficacy and safety of ivermectin used to treat or prevent COVID?19. The completed studies are small and few are considered high quality. Several studies are underway that may produce clearer answers in review updates. Overall, the reliable evidence available does not support the use of ivermectin for treatment or prevention of COVID?19 outside of well?designed randomized trials.
www.theguardian.com/science/2021/jul/16/huge-study...
Huge study supporting ivermectin as Covid treatment withdrawn over ethical concerns
The preprint endorsing ivermectin as a coronavirus therapy has been widely cited, but independent researchers find glaring discrepancies in the data
Melissa Davey
Thu 15 Jul 2021
https://www.youtube.com/watch?v=N6CJFQ_Xr7A
The science behind why Ivermectin is NOT a miracle cure for COVID
Premiered Dec 15, 2020 Debunk the Funk with Dr. Wilson
Dangerous doctors continue to spread misinformation in the midst of a pandemic. This time, it's in front of Congress. Not cool, Dr. Kory. Not cool.